Rapid relief for treatment-resistant depression
At Mind Rejuvenation in Tulsa, we offer Ketamine IV therapy as a breakthrough option for people struggling with major depressive disorder, especially when traditional treatments have not worked. Our trauma-informed, patient-centered approach keeps every step of your care safe, supportive, and tailored to your needs.
- Serving patients in Tulsa, OK
- Psychiatric evaluation before treatment
- Continuous monitoring during every session
A new option when others fall short
Ketamine was first approved by the FDA as an anesthetic. It is now gaining recognition as an off-label therapy for major depressive disorder, especially treatment-resistant depression and suicidal ideation.
At Mind Rejuvenation, we offer IV ketamine therapy in a safe, supportive environment, designed for people seeking rapid relief when conventional antidepressants have fallen short.
While ketamine shows promise in improving mood, its long-term safety and effectiveness as a mental health treatment are still being studied. It is not yet FDA-approved for depression, and its role in preventing suicide or reducing suicidal thoughts remains under clinical investigation.
Ketamine is not a substitute for hospitalization or emergency psychiatric care, nor is it intended for recreational use. If you are in immediate crisis, call 988 or go to the nearest emergency room. Every patient completes a comprehensive psychiatric evaluation before treatment begins.
We believe in personalized mental health care. When appropriate, we work closely with your psychiatrist or therapist so treatment aligns with your broader plan and you can move forward with clarity and confidence.
Not just another antidepressant
Ketamine works by targeting NMDA receptors (N-methyl-D-aspartate), key players in your brain's mood and memory pathways. By gently blocking these receptors, ketamine triggers a surge of glutamate, your brain's primary excitatory neurotransmitter.
Some patients notice improvement within hours, while others need more time or may not respond. Ketamine may also improve neuroplasticity, helping your brain adapt and form new, healthier connections.
It can also reduce inflammation in the brain, which otherwise limits how well the brain processes information and regulates neurotransmitters. Results vary by person, and your care team will help you understand what to expect.
How ketamine supports your brain
Ketamine works differently from traditional medication, which is why it may help when other options have not.
Rapid symptom relief
For some patients, ketamine therapy may provide relief within hours rather than weeks.
Enhanced neuroplasticity
It may improve your brain's capacity to adapt and change, forming new, healthier connections.
Reduced inflammation
It may help calm inflammation in the brain that can impair how you process information and regulate mood.
Conditions ketamine therapy may treat
Ketamine is emerging as a powerful option for treatment-resistant mental health and pain conditions, offering renewed hope when traditional approaches fall short. Treatment plans are personalized; eligibility is determined during your consultation.
Depression
Most widely known for reducing symptoms of major depressive disorder, especially in patients who have not responded to antidepressants. It may enhance neuroplasticity and restore healthier brain connectivity.
Anxiety
For generalized anxiety or panic symptoms, ketamine may help calm overactive neural circuits and support emotional regulation, often within hours of treatment.
Bipolar disorder
May help stabilize mood and ease depressive episodes in bipolar disorder, though it is not recommended during manic phases. Careful psychiatric oversight is essential.
Obsessive-compulsive disorder (OCD)
Still under study, ketamine has shown promise in reducing compulsive thought loops and improving cognitive flexibility in some patients with OCD.
Chronic pain
Its action on NMDA receptors can help modulate pain signals for conditions like fibromyalgia, neuropathic pain, and CRPS (Complex Regional Pain Syndrome).
PTSD
May reduce the emotional intensity of traumatic memories and support healing by easing maladaptive fear pathways and enhancing therapeutic receptivity.
Suicidal ideation
May rapidly reduce suicidal thoughts in some patients, offering a critical window for stabilization under clinical supervision. This is not emergency care.
Substance use disorders
Emerging research suggests ketamine may help disrupt addictive patterns and reduce cravings, especially when paired with behavioral therapy and relapse prevention.
Other conditions
Ketamine is also being explored for social anxiety, postpartum depression, migraines, and eating disorders. These uses are investigational and require specialized care.
Your ketamine session, step by step
Every treatment is delivered in our comfortable Tulsa clinic with strict safety protocols and continuous monitoring.
Psychiatric evaluation
You complete a comprehensive evaluation so we can confirm ketamine is medically appropriate, review your history, and make sure you are emotionally ready to begin.
Settle in
You relax in a calm, monitored setting. Plan for about two hours from arrival through observation. Our team explains what to expect before the infusion begins.
Receive your infusion
The infusion itself takes about 45 minutes, delivered slowly while our clinical team stays close and monitors your comfort and vital signs throughout.
Two-hour observation
We enforce a mandatory two-hour observation period after each infusion, with continuous monitoring and compassionate support before you leave the clinic.
Clinical expertise with compassionate care
We combine clinical expertise with compassionate, trauma-informed care. Our experienced practitioners work closely with you and your mental health team to determine if ketamine is the right fit. Every treatment is delivered in our convenient, comfortable facility with strict safety protocols.
Because ketamine therapy is not covered by insurance for depression-related use, it is offered as a self-pay service. To prioritize your safety, we enforce a mandatory two-hour observation period following each infusion, with continuous monitoring and compassionate support from our team.
Taking care of ourselves is one of the greatest gifts we can give others.
If you would prefer an insurance-covered option for treatment-resistant depression, ask your care team about SPRAVATO® nasal spray.
Learn about SPRAVATO® therapyStart your healing journey today
Whether you are ready to book your first visit or simply have questions about ketamine therapy, we are here to help. Share a few details and a member of our team will reach out shortly.
Every step you take toward wellness matters, and we are honored to walk it with you.
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