Mind Rejuvenation Tulsa


Treatments designed to alleviate symptoms of depression.


Treatments designed to alleviate symptoms of depression.

Referral Based Treatments

Mind Rejuvenation is a REMS Certified Outpatient facility providing services to all psychiatric offices and other healthcare providers.


To refer your patient for Spravato® please click the links below to download the referral form, medical release form and new patient form. Please fill out each form, print and fax the forms to us.


To refer your patient for Ketamine please click the link below to download the referral form. Please fill out the form, print and fax the forms to us.


Spravato® (esketamine) CIII Nasal Spray is the First FDA approved Ketamine-derived product covered by insurance for treatment-resistant depression. Consult with your Primary Care Physician to ensure Spravato® is the right treatment for you.

Mind Revjuvenation Spravato

What is Spravato®?

Discover an innovative treatment for depression known as Spravato® (esketamine). As the only FDA-approved nasal spray for adult patients diagnosed with Major Depressive Disorder (MDD), Spravato® offers new possibilities for those who have either been resistant to previous treatments or are experiencing suicidal thoughts or actions.

It’s important to note that Spravato® is not intended for use as a pain reliever or anesthetic medication. Its efficacy and safety as an anesthetic medicine have not been established. Furthermore, while Spravato® shows promise in managing suicidal thoughts or actions, its effectiveness in preventing suicide or reducing suicidal ideation is yet to be fully understood.

It’s crucial to remember that Spravato® should not be seen as a replacement for hospitalization if your healthcare provider deems it necessary, even if you start to experience improvement after the initial dose. Additionally, the safety and effectiveness of Spravato® have not been established in children.

Spravato® offers a new approach in the treatment of depression, providing hope for those who have struggled with conventional treatments. However, it’s essential to consult with your healthcare provider to determine if Spravato® is the right option for you, considering your specific circumstances and medical history.

Our dedicated team is here to support you and provide further information on Spravato® or any other treatment options available. Don’t hesitate to reach out and take the first step towards finding the right path to manage your depression effectively.

Benefits of Spravato®

One of the main benefits of Spravato® is that it can provide rapid relief for people with depression who have not responded to other treatment options. Many people who have used Spravato® have reported significant improvements in their symptoms within just a few hours of treatment.

In addition to providing rapid relief, Spravato® has also been shown to be effective at reducing the risk of suicidal thoughts and behaviors in people with depression. It has been approved by the FDA for use in patients who have suicidal ideation with depression, as well as for patients who have not responded to at least two other treatment options.

Overall, Spravato® is a promising treatment option for people with depression who have not found relief with other treatments. If you are interested in learning more about Spravato® and whether it may be right for you, we recommend speaking with a healthcare professional.

What to Expect with Spravato®



Used in small doses for the treatment of depression.

Possible Benefits

Mind Revjuvenation Ketamine IV Therapy

What is Ketamine?

Experience the potential breakthrough in depression treatment with Ketamine. Approved by the FDA for anesthetic purposes, Ketamine has also emerged as an off-label option for patients facing treatment resistance and struggling with suicidal thoughts in the context of major depressive disorder.

It’s important to note that the safety and effectiveness of Ketamine as a depression medication are still under investigation. Furthermore, its efficacy in preventing suicide or reducing suicidal thoughts or actions is yet to be fully established.

Ketamine is not intended as a substitute for hospitalization or recreational purposes. Before, during, and after Ketamine treatment, all patients are required to undergo a comprehensive assessment and consultation with their psychiatric provider to ensure suitability and safety. Please be aware that insurance payers have not yet approved Ketamine for use in major depressive disorder, making Ketamine services a self-pay benefit for our patients.

To prioritize patient well-being, a mandatory two-hour observational period is strictly enforced following each Ketamine treatment. Our dedicated team is committed to guiding you through this transformative process, ensuring your utmost care and providing ongoing support.

Together, let’s explore the potential of Ketamine as a treatment option, while working hand in hand with your psychiatric provider to tailor the most effective approach for your specific needs. We understand the importance of personalized care in your journey toward relief from the burdens of depression.

Benefits of Ketamine

Understanding the science behind Ketamine sheds light on its remarkable benefits as a treatment for depression. Ketamine primarily targets the NMDA receptors in the brain. By binding to these receptors, Ketamine triggers an increase in the levels of glutamate, a vital neurotransmitter, in the spaces between neurons. Consequently, this activation prompts another set of receptors called AMPA receptors to engage. The dual action of blocking NMDA receptors and activating AMPA receptors plays a crucial role in enhancing neuron communication, facilitating the formation of new pathways. This fascinating process, known as synaptogenesis, leads to heightened levels of “happy chemicals” such as Dopamine and Serotonin in the brain, which profoundly influence mood, thought patterns, and cognition. Moreover, Ketamine may further contribute to alleviating depression by diminishing the signals associated with inflammation. By reducing inflammation, Ketamine promotes improved communication within specific regions of the brain, thereby potentially enhancing its effectiveness as a treatment option.

Ketamine IV treatment offers a remarkable approach for fast relief from depression, as small doses of Ketamine are directly delivered into the bloodstream. This method is particularly beneficial for individuals with treatment-resistant depression who have found little success with other medications. By bypassing traditional treatment limitations, Ketamine IV provides a renewed sense of hope for those seeking rapid and effective relief from the burdens of depression.

Prescribed Treatment

To get Ketamine infusion prescribed as a treatment, individuals will need to visit a healthcare professional, such as a doctor or nurse practitioner, who is certified to prescribe the medication. During the visit, the healthcare professional will assess the individual’s symptoms and medical history to determine whether Ketamine infusion is an appropriate treatment option.

If the healthcare professional determines that Ketamine infusion is a suitable treatment, they will write a prescription for the medication and provide instructions on how to use it safely and effectively. It is important to follow the healthcare professional’s instructions and any warnings on the medication label carefully.

It is also important to note that Ketamine is a controlled substance and is only available through a restricted distribution system. This means that it must be prescribed and dispensed by a certified healthcare professional and must be used in a certified treatment center such as Mind Rejuvenation.

If you are interested in exploring Ketamine infusion treatment as a treatment option for your depression, we recommend talking to a healthcare professional to determine whether it is right for you.

Depression & How Ketamine Therapy Works

How Depression Affects the Brain

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